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Of interest, mature OL clusters expressing genes suggestive of immune function have been identified, for example supporting an MHC-class II-mediated response 71

As ibrutinib had no direct effect upon astrocytes, this may be explained by further glial cell crosstalk (182)

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Targeted analysis was performed using the same chromatographic conditions but with the instrument operating in a parallel reaction monitoring (PRM) method in which targeted HCD MS2 scan were acquired on 12 precursor ions, corresponding to 3 proteins, using an isolation windows of 0.7 m/z (Supplementary Data 1)

Another recent retrospective study showed promising results when comparing fecal microbiota transplantation to an oral treatment consisting of dietary and lifestyle changes, pre- and probiotics, and natural remedies